abstract：:β-N-Acetylhexosaminidases (CAZy GH20, EC 3.2.1.52) are exo-glycosidases specific for cleaving N-acetylglucosamine and N-acetylgalactosamine moieties of various substrates. The β-N-acetylhexosaminidase from the filamentous fungus Talaromyces flavus (TfHex), a model enzyme in this study, has a broad substrate flexibilit...

journal_title：International journal of biological macromolecules

authors： Kapešová J,Petrásková L,Kulik N,Straková Z,Bojarová P,Markošová K,Rebroš M,Křen V,Slámová K

更新日期：2020-10-15 00:00:00

abstract：:Recently low-molecular lignin was reported to activate lytic polysaccharide monooxygenases (LPMOs) to oxidize cellulose. However, whether lignin formed in cell wall can play the role as electron donor for LPMOs is still largely unknown due to the complex ultrastructure of lignocellulosic biomass. In this study, we pre...

journal_title：International journal of biological macromolecules

authors： Ni H,Li M,Li F,Wang L,Xie S,Zhang X,Yu H

更新日期：2020-10-15 00:00:00

abstract：:Cyclina sinensis is an edible clam widely distributed along the coastal waters of Asia. In the present study, a polysaccharide (CSP-1) isolated from C. sinensis was purified by a DEAE-Sepharose Fast Flow column, and it had an average molecular weight of 3.8 × 105 Da and a prevalent component monosaccharide of Glc. The...

journal_title：International journal of biological macromolecules

authors： Gong Y,Cao C,Ai C,Wen C,Wang L,Zhao J,Han Y,Song S,Xiao H

更新日期：2020-10-15 00:00:00

abstract：:In this paper, the electronspun Polylactic acid (PLA)/TiO2 nanofluids (nfs) fibrous membrane with good toughness, hydrophilicity and antibacterial activities are fabricated by taking full advantages of solvent-free TiO2 nfs with amphiphilicity and ionic conductivity. The resulting PLA/TiO2 nfs fibrous membrane exhibit...

journal_title：International journal of biological macromolecules

authors： Yu Q,Qin Y,Han M,Pan F,Han L,Yin X,Chen Z,Wang L,Wang H

更新日期：2020-10-15 00:00:00

abstract：:While the cashew culture is focused on processing and commercialization of cashew nuts, the pseudofruit (cashew apples) - highly perishable and of limited acceptance - are mostly wasted. The cashew tree pruning fiber (CTPF) is another interesting cashew byproduct. In this study, films have been made from bacterial cel...

journal_title：International journal of biological macromolecules

authors： Sá NMSM,Mattos ALA,Silva LMA,Brito ES,Rosa MF,Azeredo HMC

更新日期：2020-10-15 00:00:00

abstract：:Epilobium is a medicinal plant; its extracts are widely used traditional medicine due to their broad range of pharmacological and therapeutic properties. Its most prominent feature is its therapeutic effects on prostatic diseases. The aim of this study is preparation of controlled release system of Epilobium parviflor...

journal_title：International journal of biological macromolecules

authors： Egil AC,Ozdemir B,Gok B,Kecel-Gunduz S,Budama-Kilinc Y

更新日期：2020-10-15 00:00:00

abstract：:Guava seed polysaccharide fraction 3 (GSF3) is an immunomodulatory polysaccharide from guava (Psidium guajava L.) seed polysaccharides. However, effects of GSF3 on the growth of breast cancer cells were not understood, yet. To clarify the GSF3 effects on breast cancer cell growth, GSF3 was subjected to treat MCF-7 cel...

journal_title：International journal of biological macromolecules

authors： Lin HC,Lin JY

更新日期：2020-10-15 00:00:00

abstract：:Albumin and hyaluronic acid are biodegradable, endogenous substances with potential use as drug carriers. These properties combined with the physical structure of the gel can lead to the formation of biologically active materials with application in medicine. This work investigated the gelation process of albumin solu...

journal_title：International journal of biological macromolecules

authors： Hájovská P,Chytil M,Kalina M

更新日期：2020-10-15 00:00:00

abstract：:Two cucumber F1 cultivar hybrids were investigated for stress tolerance markers upon application of different strength of Hoagland fertigation solutions (HG). 'Joker' and 'Oitol' cultivar hybrids were studied, representing typically field grown and greenhouse cultivated genotypes, respectively. At standard fertigation...

journal_title：International journal of biological macromolecules

authors： Oszlányi R,Mirmazloum I,Pónya Z,Szegő A,Jamal S,Bat-Erdene O,Papp I

更新日期：2020-10-15 00:00:00

abstract：:Broken-rice starch nanoparticles with different mean particle diameters for 100, 200, 400 and 800 nm were prepared by nanoprecipitation, alkali freezing, cross-linking and H2SO4 hydrolysis methods respectively, and their structural, morphological and physicochemical properties were systematically characterized. The re...

journal_title：International journal of biological macromolecules

authors： Xiao H,Yang F,Lin Q,Zhang Q,Zhang L,Sun S,Han W,Liu GQ

更新日期：2020-10-01 00:00:00

abstract：:Codonopsis pilosula polysaccharide (CPPS) and selenizing CPPS (sCPPS) were prepared and identified by a combination of chemical and instrumental analysis. Their immune modulation activities were compared by lymphocyte proliferation and flowcytometry tests in vitro or serum antibody responses and cytokines with immuniz...

journal_title：International journal of biological macromolecules

authors： Gao Z,Zhang C,Jing L,Feng M,Li R,Yang Y

更新日期：2020-10-01 00:00:00

abstract：:In order to exploit an abundant and cheap carbon source for poly(3-hydroxybutyrate) (PHB) production, the rice husk was pretreated with dilute sulfuric acid and steam flash-explosion to enhance the enzymatic saccharification. The yield of reducing sugars of pretreated rice husk hydrolysate came up to 266.5 mg/g rice h...

journal_title：International journal of biological macromolecules

authors： Zhang Y,Wang L,Li T,Shen Y,Luo J

更新日期：2020-10-01 00:00:00

abstract：:In this study, chitosan and gelatin materials incorporated with grape seed (Vitis vinifera L.) (VSE) and jabuticaba peel (Plinia cauliflora) (PPE) extracts were developed with potential application as food coatings. It was evaluated how the concentration of the extracts and their addition order in the polymeric matrix...

journal_title：International journal of biological macromolecules

authors： Rodrigues MÁV,Bertolo MRV,Marangon CA,Martins VDCA,Plepis AMG

更新日期：2020-10-01 00:00:00

abstract：:In this study, the inhibitory effects of four anthraquinones including chrysophanol, emodin, physcione and rhein on tyrosinase were investigated by enzyme inhibition assay. The results indicated that all of anthraquinones could significantly inhibit the activity of tyrosinase in a competitive manner. To gain insight i...

journal_title：International journal of biological macromolecules

authors： Zeng HJ,Sun DQ,Chu SH,Zhang JJ,Hu GZ,Yang R

更新日期：2020-10-01 00:00:00

abstract：:The objective of this study was to improve the compatibility between poly(lactic acid) (PLA) and thermoplastic starch (TPS) in PLA/TPS blown films by incorporating oligo(lactic acid)-grafted starch (OLA-g-starch) as a compatibilizer. OLA-g-starch with a degree of substitution of 1.2 and degree of polymerization of 2.0...

journal_title：International journal of biological macromolecules

authors： Noivoil N,Yoksan R

更新日期：2020-10-01 00:00:00

abstract：:Yellow horn (Xanthoceras sorbifolia Bunge) is a oil-rich, woody deciduous shrub with exceptional economic and ecological values. Basic Helix-Loop-Helix (bHLH) transcription factor (TF) family fulfills crucial biological functions in plant. However, genome-wide survey of the bHLH genes in yellow horn has not been perfo...

journal_title：International journal of biological macromolecules

authors： Lang Y,Liu Z

更新日期：2020-10-01 00:00:00

abstract：:To improve the thermostability of r27RCL from Rhizopus chinensis and broaden its industrial applications, we used rational design (FoldX) according to ΔΔG calculation to predict mutations. Four thermostable variants S142A, D217V, Q239F, and S250Y were screened out and then combined together to generate a quadruple-mut...

journal_title：International journal of biological macromolecules

authors： Wang R,Wang S,Xu Y,Yu X

更新日期：2020-10-01 00:00:00

abstract：:In this paper, selenized Artemisia sphaerocephala polysaccharides (SePAS) were obtained through employing N-methyl-2-pyrrolidone hydrosulfate as catalyst, which showed a maximum Se content enhanced to 8744 μg/g. FT-IR, 1D/2D NMR, X-ray photoelectron spectroscopy (XPS) and size-exclusion chromatograph analysis exhibite...

journal_title：International journal of biological macromolecules

authors： Li R,Qin X,Liu S,Zhang X,Zeng X,Guo H,Wang T,Zhang Y,Zhang J,Zhang J,Wang J

更新日期：2020-10-01 00:00:00

abstract：:Sago pith cellulose nanofibril (SPCNF) aerogel derived from sago pith waste (SPW) was successfully produced through three consecutive steps, namely dewaxing and delignification, ultra-sonication and homogenization and freeze drying. The aerogel was characterized using field emission scanning electron microscopy (FE-SE...

journal_title：International journal of biological macromolecules

authors： Beh JH,Lim TH,Lew JH,Lai JC

更新日期：2020-10-01 00:00:00

abstract：:Biocompatible soy protein isolate/silk fibroin (SPI/SF) nanofibrous scaffolds were successfully fabricated through electrospinning a novel protein blend SPI/SF. Prepared nanofibers were treated with ethanol vapor to obtain an improved water-stable structure. Fabricated scaffolds were characterized through scanning ele...

journal_title：International journal of biological macromolecules

authors： Varshney N,Sahi AK,Poddar S,Mahto SK

更新日期：2020-10-01 00:00:00

abstract：:Indian cobra (Naja naja) envenomation is frequently reported across Indian subcontinent. Geographical differences in the venom composition of a particular species of snake often leads to inconsistencies in the antivenom neutralization. Consequently, determining the venom proteome from every locale is necessary for the...

journal_title：International journal of biological macromolecules

authors： Chanda A,Mukherjee AK

更新日期：2020-10-01 00:00:00

abstract：:Donepezil (DPZ) is a well-known drug for Alzheimer's disease that inhibits acetylcholinesterase activity (AChE). In the present study, the inhibitory effect of DPZ on non-enzymatic glycated-AChE (GLY-AChE) was studied by different experimental and simulation techniques. The initial investigation revealed that glycatio...

journal_title：International journal of biological macromolecules

authors： Yekta R,Sadeghi L,Dehghan G

更新日期：2020-10-01 00:00:00

abstract：:Cysteine-Rich Secretory Proteins (CRISP) are widespread in snake venoms and known to target ion channels. More recently, CRISPs have been shown to mediate inflammatory responses. Involvement of potential receptor in CRISP-induced inflammatory reactions, however, remains unknown. A CRISP protein named as Nk-CRISP, was ...

journal_title：International journal of biological macromolecules

authors： Deka A,Sharma M,Mukhopadhyay R,Devi A,Doley R

更新日期：2020-10-01 00:00:00

abstract：:It is necessary to use chemical crosslinking to regulate the mechanical properties, biodegradability and biocompatibility of hydrogels. In this study, three kinds of collagen type I (Col I)/hyaluronic acid (HA) hydrogels with the same ratio and different chemical crosslinking manners were designed and fabricated, and ...

journal_title：International journal of biological macromolecules

authors： Kong W,Gao Y,Liu Q,Dong L,Guo L,Fan H,Fan Y,Zhang X

更新日期：2020-10-01 00:00:00

abstract：:Understanding the factors governing stability of proteins is fundamentally and industrially important topic in protein science. Bacterial alpha amylases are industrially important enzymes which are involved in the breakage of α-1, 4-glycosidic bonds in starch. Current study is focussed on elucidating the role of non-c...

journal_title：International journal of biological macromolecules

authors： Ahmad A,Mishra R

更新日期：2020-09-15 00:00:00

abstract：:Although the anti-diabetic properties of Konjac glucomannan (KGM) have been reported previously; however, the molecular pathways of its anti-diabetic properties are not clear. The present study hypothesized that KGM could mitigate oxidative stress and inflammation. Three doses of KGM (40, 80, 120 mg/kg b.w.) decreased...

journal_title：International journal of biological macromolecules

authors： Zhao Y,Jayachandran M,Xu B

更新日期：2020-09-15 00:00:00

abstract：:The genus Cnidoscolus (Euphorbiaceae) is widely distributed in tropical areas. In the Northeast of Brazil, the species C. quercifolius is endemic and has been used in traditional medicine. In this study, a novel protein was isolated from C. quercifolius seeds and characterized by its molecular weight, primary structur...

journal_title：International journal of biological macromolecules

authors： Moura LFWG,da Silva Costa HP,da Silva Neto JX,Dias LP,Magalhães FEA,van Tilburg MF,Florean EOPT,de Oliveira JTA,Oliveira Bezerra de Sousa D,Guedes MIF

更新日期：2020-09-15 00:00:00

abstract：:New details of chemical structure of Araucaria lignin are the focus of this paper, since Araucaria is a relict plant which fossils are dated by the Permian period. Quantitative chemical analysis, FTIR, EPR and 2D NMR spectroscopies, Py-GC/MS and nitrobenzene oxidation have been used to characterize the Araucaria ligni...

journal_title：International journal of biological macromolecules

authors： Kocheva LS,Karmanov AP,Mironov MV,Belyy VA,Polina IN,Pokryshkin SA

更新日期：2020-09-15 00:00:00

abstract：:Herein, following the strategy of sustainable, environment protection, circular economy development, carboxylate-modification lignosulfonate polymer (M-LSP) was synthesized from lignosulfonate by solvent-free esterifying with maleic anhydride (MA) by one step, and was used to remove the dyes by adsorption. FT-IR and X...

journal_title：International journal of biological macromolecules

authors： Tang Y,Lin T,Ai S,Li Y,Zhou R,Peng Y

更新日期：2020-09-15 00:00:00

abstract：:Among the various types of polyhydroxyalkanoate (PHA), poly[(R)-3-hydroxybutyrate-co-(R)-3-hydroxyhexanoate] [P(3HB-co-3HHx)] has a high potential to serve as commercial bioplastic due to its striking resemblance to petroleum-based plastics. In this study, five different genotypes of Cupriavidusnecator transformants h...

journal_title：International journal of biological macromolecules

authors： Tan HT,Chek MF,Lakshmanan M,Foong CP,Hakoshima T,Sudesh K

更新日期：2020-09-15 00:00:00

abstract：:CD117/c-kit, a tyrosine kinase receptor, plays a critical role in hematopoiesis, pigmentation, and fertility. The overexpression and activation of c-kit are thought to promote tumor growth and have been reported in various cancers, including leukemia, glioblastoma and mastocytosis. To disrupt the SCF/c-kit signaling a...

journal_title：International journal of biological macromolecules

authors： Kim JO,Kim HN,Kim KH,Baek EJ,Park JY,Ha K,Heo DR,Seo MD,Park SG

更新日期：2020-09-15 00:00:00

abstract：:Although synthetic CpG oligodeoxynucleotides (ODNs) have shown substantial potential as immunotherapeutic agents, their effective intracellular delivery remains challenging. In this work, nanoparticles prepared from low-molecular weight (LMW) chitosans were investigated as CpG ODN delivery systems. Chitosan samples wi...

journal_title：International journal of biological macromolecules

authors： Babii O,Wang Z,Liu G,Martinez EC,van Drunen Littel-van den Hurk S,Chen L

更新日期：2020-09-15 00:00:00

abstract：:In this work, graft-copolymerization of poly vinylpyrollidone onto Azadirachta indica gum polysaccharide in the presence of crosslinker has been carried out to prepare the hydrogel for use in drug delivery. The polymers were characterized by cryo-SEM, AFM, FTIR, and 13C NMR. The gel strength, cross-link density, mesh ...

journal_title：International journal of biological macromolecules

authors： Singh B,Singh B

更新日期：2020-09-15 00:00:00

abstract：:The present research was concerned with preparation of mesoporous starch (MPS) as a carrier for genistein, a model of poorly water-soluble phytoestrogen isoflavone; and exploration of the impact of different fabrication parameters on structural and loading properties. MPS is considered as a highly porous biomaterial w...

journal_title：International journal of biological macromolecules

authors： Soleimanpour M,Tamaddon AM,Kadivar M,Abolmaali SS,Shekarchizadeh H

更新日期：2020-09-15 00:00:00

abstract：:Human malaria is a pathogenic disease mainly caused by Plasmodium falciparum, which was responsible for about 405,000 deaths globally in the year 2018. To date, several vaccine candidates have been evaluated for prevention, which failed to produce optimal output at various preclinical/clinical stages. This study is ba...

journal_title：International journal of biological macromolecules

authors： Pritam M,Singh G,Swaroop S,Singh AK,Pandey B,Singh SP

更新日期：2020-09-01 00:00:00

abstract：:In this study, in order to evaluate influences of different drying methods on the structural characteristics, physicochemical properties and antioxidant activities of exopolysaccharides (EPS) from Lactobacillus helveticus MB2-1, three drying methods, including spray-drying (SD), freeze-drying (FD) and spray freeze-dry...

journal_title：International journal of biological macromolecules

authors： Xiao L,Li Y,Tian J,Zhou J,Xu Q,Feng L,Rui X,Fan X,Zhang Q,Chen X,Dong M,Li W

更新日期：2020-08-15 00:00:00

abstract：:Three anionic chitosan surfactant with different hydrophobic tails labeled Chitosan-R8, Chitosan-R12 and Chitosan-R16 were prepared and their surface behavior in aqueous solution was determined by surface tension measurements at three different temperatures 20, 40 and 60 °C. The affinity of the synthesized anionic chi...

journal_title：International journal of biological macromolecules

authors： Badr EA,Hefni HHH,Shafek SH,Shaban SM

更新日期：2020-08-15 00:00:00

abstract：:Hardwood Kraft lignin (HKL)-based ultrafine carbon fibers with different pore structures and properties were prepared by controlling the intermolecular interaction between HKL and incorporated poly(ethylene glycol)-block-poly(propylene glycol)-block-poly(ethylene glycol) (PEG-PPG-PEG) triblock copolymer. The thermal p...

journal_title：International journal of biological macromolecules

authors： Wang S,Innocent MT,Chen J,Wang Q,Ma W,Tang J

更新日期：2020-08-15 00:00:00

abstract：:Protic ionic liquids have been proposed as effective solvents for the selective extraction of lignin from wood. In this work, the protic ionic liquid 1-methylimidazolium chloride has been used to extract lignin at different biomass loadings, temperatures, and times to understand the influence of treatment severity on ...

journal_title：International journal of biological macromolecules

authors： Ovejero-Pérez A,Rigual V,Domínguez JC,Alonso MV,Oliet M,Rodriguez F

更新日期：2020-08-15 00:00:00

abstract：:In the present study, we investigated the neuroprotective effects of a purified Corydalis yanhusuo polysaccharide (CYP) on Aβ (25-35)-induced neurotoxicity and explored its underlying molecular mechanisms in PC12 cells. The results showed pretreatment with CYP (25, 50, and 100 μg/ml) prior to Aβ (25-35) exposure signi...

journal_title：International journal of biological macromolecules

authors： He Y,Xu W,Qin Y

更新日期：2020-08-15 00:00:00